Platform

Compelling clinical data

fuels our platform

The microbiome:
Essential for health.
Harnessed for medicine.

The microbiome consists of trillions of microbes that live symbiotically in and on every human and are essential to our health. When key microbes are lost, the resulting microbiome disruption can increase susceptibility to immune disorders, infections, neurological conditions, cancer, and other serious conditions. We aim to leverage our Human-First Discovery^® platform to develop novel therapeutics designed to deliver missing microbes and their clinically relevant biochemical functions to correct microbiome disruption and the conditions that emerge from it.

Our Human-First Discovery platform

Our platform is fueled by data from human microbiota transplantation studies. These studies involve the transfer of microbiota from healthy individuals to individuals with disease, an area of intense research with hundreds of studies spanning dozens of different conditions. We leverage data from these types of studies to identify conditions where a disrupted microbiome is driving disease and to uncover the key dynamics associated with successful clinical outcomes.

Platform highlights:

Lead asset supported by positive Phase 2 placebo-controlled and open-label data in recurrent CDI

Differentiated discovery process, with proof-of-principle clinical data leveraged to guide product design

Finch aims to harness full diversity and potential of the microbiome, with additional assets targeting autism and IBD

An industry leading IP portfolio

Finch’s platform and pipeline is protected by a leading patent portfolio with significant longevity and broad relevance for the industry.

Extensive, multi-layered
patent protection

>55 issued U.S. and foreign patents and >140 patent applications pending
Robust protection for lead candidate through 2036

Foundational patents
in the field

Priority dates of foundational patent family predate the industry, enabling broad protection for composition of matter, methods of use, manufacture, and formulation claims through 2031

Broad & diverse
patent protection

Protection for multiple microbiome product strategies, including donor-derived and donor-independent product strategies
Diverse therapeutic coverage, with protection for a wide range of indications of interest

View patents

SELECT U.S. PATENTS INCLUDE:

Dec 28, 2021 – Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them (11,207,356)

Dec 21, 2021 – Methods for treating autism spectrum disorder and associated symptoms (11,202,808**)

Nov 16, 2021 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering Them (11,173,183)

Nov 9, 2021 – Methods and Compositions for Treating Ulcerative Colitis (11,166,990)

Sep 28, 2021 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering Them (11,129,859)

Sep 21, 2021 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Device for Delivering Them (11,123,377)

Aug 31, 2021 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering Them (11,103,541)

Jul 27, 2021 – Methods for Treating Ulcerative Colitis (11,071,759)

Jul 20, 2021 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering Them (11,065,284)

Apr 27, 2021 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering Them (10,987,385)

Dec 8, 2020 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering Them (10,857,188)

Dec 1, 2020 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering Them (10,849,937)

Dec 1, 2020 – Compositions and Methods for C. difficile Treatment (10,849,936*)

Nov 3, 2020 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Device for Delivering Them (10,821,138)

Jun 9, 2020 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering Them (10,675,309)

Apr 14, 2020 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering Them (10,617,724)

Apr 7, 2020 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering Them (10,610,551)

Feb 18, 2020 – Methods for Treating Ulcerative Colitis (10,561,690)

Nov 5, 2019 – Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them (10,463,702)

Jun 25, 2019 – Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them (10,328,107)

May 14, 2019 – Compositions and methods for transplantation of colon microbiota (10,286,011*)

May 14, 2019 – Compositions and methods for transplantation of colon microbiota (10,286,012*)

May 7, 2019 – Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them (10,278,997)

Apr 9, 2019 – Compositions and methods for transplantation of colon microbiota (10,251,914*)

Feb 5, 2019 – Methods for Treating Ulcerative Colitis (10,195,235)

Sep 4, 2018 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering Them (10,064,899)

Jul 24, 2018 – Compositions and Methods for Transplantation of Colon Microbiota (10,028,980*)

Jul 17, 2018 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering Them (10,022,406)

May 15, 2018 – Compositions and Methods for Transplantation of Colon Microbiota (9,968,638*)

May 8, 2018 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering Them (9,962,413)

Feb 27, 2018 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Device for Delivering Them (9,901,603)

Aug 1, 2017 – Microbiome Markers and Therapies for Autism Spectrum Disorders (9,719,144***)

May 16, 2017 – Compositions and Methods for Transplantation of Colon Microbiota (9,649,343*)

Apr 12, 2016 – Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering Them (9,308,226)

*Patents are exclusively licensed by Finch from the Regents of the University of Minnesota.

**Patent is jointly owned with, and exclusively licensed from, the Arizona Board of Regents on behalf of Arizona State University and the Regents of the University of Minnesota.

***Patent exclusively licensed by Finch from the Arizona Board of Regents on behalf of Arizona State University.